LabSense

Non-HDL Cholesterol: A Powerful, Practical Target Especially When Triglycerides Are High

9/4/2025

Non-HDL cholesterol equals Total cholesterol − HDL. It captures all atherogenic particles (VLDL, IDL, LDL). People search: "non HDL 160", "apoB vs non-HDL". When triglycerides are elevated, non-HDL is often more robust than LDL alone.

Typical targets (education)

  • For many risk categories, non-HDL target is roughly LDL goal + 30 mg/dL (varies by guideline).
  • ApoB is another strong measure; many clinics use either depending on availability.

How to lower non-HDL

  • Lifestyle: fiber, plant sterols, weight management, physical activity, stop smoking.
  • Discuss medications when indicated: statins first-line; consider ezetimibe or PCSK9 inhibitors for additional lowering.

Educational use only. Not a treatment plan.

Educational information only — not a diagnosis, treatment, or prescription.