Urinalysis Basics: Protein, Blood, Nitrite/Leukocyte Esterase, Specific Gravity, and Microscopy
9/7/2025
A urinalysis (UA) adds context to kidney and urinary symptoms. People search: "protein in urine", "trace blood in urine", "nitrite positive". Technique matters: use a clean-catch midstream sample to avoid contamination.
Dipstick highlights
- Protein: confirm with albumin/creatinine ratio (ACR) for chronic detection and staging.
- Blood: can detect hemoglobin/myoglobin; confirm red cells on microscopy.
- Nitrite/LE: suggest gram-negative bacteriuria; interpret with symptoms before treating.
- Specific gravity: hydration and concentrating ability.
- Glucose/ketones: think diabetes control or fasting/ketogenic states.
Microscopy pearls
- RBC morphology and casts can point toward glomerular disease.
- WBCs and bacteria support infection; epithelial cells suggest contamination.
Educational next steps
- For chronic proteinuria or hematuria, discuss kidney evaluation, blood pressure control, and repeat testing.
- For UTI symptoms, cultures guide therapy; avoid antibiotics for asymptomatic bacteriuria except in specific scenarios.
Educational use only. Not medical advice.
Educational information only — not a diagnosis, treatment, or prescription.