LabSense

Urinalysis Basics: Protein, Blood, Nitrite/Leukocyte Esterase, Specific Gravity, and Microscopy

9/7/2025

A urinalysis (UA) adds context to kidney and urinary symptoms. People search: "protein in urine", "trace blood in urine", "nitrite positive". Technique matters: use a clean-catch midstream sample to avoid contamination.

Dipstick highlights

  • Protein: confirm with albumin/creatinine ratio (ACR) for chronic detection and staging.
  • Blood: can detect hemoglobin/myoglobin; confirm red cells on microscopy.
  • Nitrite/LE: suggest gram-negative bacteriuria; interpret with symptoms before treating.
  • Specific gravity: hydration and concentrating ability.
  • Glucose/ketones: think diabetes control or fasting/ketogenic states.

Microscopy pearls

  • RBC morphology and casts can point toward glomerular disease.
  • WBCs and bacteria support infection; epithelial cells suggest contamination.

Educational next steps

  1. For chronic proteinuria or hematuria, discuss kidney evaluation, blood pressure control, and repeat testing.
  2. For UTI symptoms, cultures guide therapy; avoid antibiotics for asymptomatic bacteriuria except in specific scenarios.

Educational use only. Not medical advice.

Educational information only — not a diagnosis, treatment, or prescription.